as we cannot change the larger situation, why don’t we do x? / doing x is probably our best choice

You don’t have to be at work for another week. You may as well take a trip somewhere while you can.

I’m going to be here for a while. You may as well get used to it.

We’re going to be waiting here for a while. We may as well play a game.

Since we have been paired together, we may as well try to work together.